Helios packs 72 MI455X GPUs and Venice CPUs in a $5M+ rack competing with NVIDIA NVL72 — AMD's biggest AI infrastructure bet. AnthropicAn AI safety company — creators of the Claude family of language models. committed to up to 2 gigawatts of MI450 GPUs; OpenAIAn AI research company — created GPT, ChatGPT, DALL-E, and the o-series reasoning models. said it had run GPTGenerative Pre-trained Transformer — OpenAI's family of large language models from GPT-1 through GPT-5. workloads on Helios for three months — shifting the AI hardware story beyond NVIDIA Blackwell.

Helios gave frontier labs a shipping alternative to NVIDIA rack-scale AI systems.

Multi-gigawatt AMD deals diversified who could supply training and inferenceRunning a trained model to produce predictions — as opposed to the training phase that learns weights. at scale.